Centile nomograms for body weight and length of multiple-birth infants
K.R. Bondarenko1, P.A. Kuznetsov1–3, L.S. Dzhokhadze1, V.V. Lyan1, A.V. Kriger1, E.S. Eletnova1
1Pirogov Russian National Research Medical University, Moscow, Russian Federation
2City Clinical Hospital No. 24, Moscow, Russian Federation
3Research Institute of Public Health Organization and Medical Management, Moscow, Russian Federation
Anthropometric screening of body weight and length is one of the first steps of infant’s health assessment. However, nomograms for multiple-birth infants are badly regulated and were not reviewed for a long time.
Aim: to develop body weight and length nomograms for twin infants.
Patients and Methods: the study was performed in three obstetrical inpatient departments located in various Moscow districts. Data on
52 357 infants born in 2015–2017 (50 555 singleton-birth infants and 1802 multiple-birth infants) were analyzed. Study group included 1802 infants (901 twins) born at 22–40 weeks of gestation. These infants were divided into 2 subgroups. Subgroup I included 158 monochorionic twins and subgroup II included 743 dichorionic twins. Control group included 50.555 singleton-birth infants born at 22–42 weeks of gestation.
Results: body weight and length of twin infants are similar to these of singleton-birth infants up to 30 weeks of gestation. After 30 weeks of gestation, this difference progressively increases both in boys and girls. Twin growth discordance (weight difference >20%) is of particular interest. Dissociation of twin development is associated with higher rate of complications. However, it’s only fair when smaller twin growth is restricted.
Conclusions: anthropometric parameters of multiple-birth and singleton-birth infants are different. Fetal weight less than 10th percentile for a certain term by adjusted nomograms for twins is the criterion for fetal growth restriction. Therefore, nomograms for multiple-birth children should be regulated and approved. Diagnostic criteria for fetal growth restriction in multiple pregnancy should be reviewed according to our nomograms for twins to prevent overdiagnosis of this obstetrical complication.
Keywords: multiple pregnancy, twins, nomograms, dissociation, fetal growth restriction.
For citation: Bondarenko K.R., Kuznetsov P.A., Dzhokhadze L.S. et al. Centile nomograms for body weight and length of multiple-birth infants. Russian Journal of Woman and Child Health. 2020;3(1):–25. DOI: 10.32364/2618-8430-2020-3-1-20-25.
About the authors:
1Karina R. Bondarenko — MD, PhD, Assistant Professor of the Department of Obstetrics and Gynecology, ORCID ID 0000-0003-4147-1151;
1–3Pavel A. Kuznetsov — MD, PhD, Assistant Professor of the Department of Obstetrics and Gynecology, ORCID ID 0000-0003-2492-3910;
1Lela S. Dzhokhadze — MD, PhD, Assistant of the Department of Obstetrics and Gynecology, ORCID ID 0000-0001-5389-7817;
1Victoria V. Lyan — student of the 6th course of Medical Faculty, ORCID ID 0000-0003-4830-6052;
1Anna V. Kriger — student of the 6th course of Medical Faculty, ORCID ID 0000-0001-6823-2658;
1Ekaterina S. Eletnova — student of the 6th course of Medical Faculty, ORCID ID 0000-0002-8857-9779.
1Pirogov Russian National Research Medical University. 1, Ostrovityanov str., Moscow, 117437, Russian Federation.
2City Clinical Hospital No. 24. 4, Vyatskiy Lane, Moscow, 127287, Russian Federation.
3Research Institute of Public Health Organization and Medical Management. 9, Sharikopodshipnikovskaya str., Moscow, 15088, Russian Federation.
Contact information: Karina R. Bondarenko, e-mail: email@example.com. Financial Disclosure: no authors have a financial or property interest in any material or method mentioned. There is no conflict of interests. Received 28.10.2019.
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